炔诺肟酯

中文名称:

炔诺肟酯

中文同义词:

诺孕脂;诺孕酮杂质;炔诺肟酯溶液, 100PPM;诺孕酯NORGESTIMATE;炔诺肟酯;诺孕酯;诺孕酪;炔诺圬酯

英文名称:

Norgestimate

英文同义词:

13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl acetate;(17R)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one oxime;Norgestimate (200 mg);(17α)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-OxiMe;(17a)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-Oxime;D-138;(17-alpha)-17-(acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one3-oxime;18,19-dinorpregn-4-en-20-yn-3-one,17-(acetyloxy)-13-ethyl-,3-oxime,(17-alpha

CAS号:

35189-28-7

分子式:

C23H31NO3

分子量:

369.5

EINECS号:

相关类别:

医药原料;原料药;原料药;Metabolite Reference Standard;Isotopically Labeled Pharmaceutical Reference Standard;VAGISTAT;Hormone;Intermediates Fine Chemicals;Pharmaceuticals;Steroids

Mol文件:

35189-28-7.mol

熔点 

216°C

比旋光度 

D25 +110°

沸点 

497.9±45.0 °C(Predicted)

密度 

1.22±0.1 g/cm3(Predicted)

储存条件 

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

溶解度 

DMSO: soluble5mg/mL (clear solution)

酸度系数(pKa)

12.21±0.60(Predicted)

形态

powder

颜色

white to beige

旋光性 (optical activity)

[α]/D 43±3°, c = 1 in chloroform

BRN 

6440219

CAS 数据库

35189-28-7

EPA化学物质信息

18,19-Dinorpregn-4-en-20-yn-3-one, 17-(acetyloxy)-13-ethyl-, 3-oxime, (17.alpha.)- (35189-28-7)

生物活性

Norgestimate 是一种合成的孕激素类似物，一种具有口服活性，高度选择性的孕激素活性和最小雄激素作用的孕激素 (progestin)。Norgestimate 可用于口服避孕药。

体外研究

Norgestimate is converted to at least two active metabolites: levonorgestrel 3-oxime (deacetylated norgestimate; norelgestromin) and levonorgestrel.

化学性质 

白色或类白色结晶粉末

危险品标志 

Xn

危险类别码 

63-22-36/38-62

安全说明 

26-36/37

WGK Germany 

3

RTECS号

JF7976000

海关编码 

2937230000