3,4-二羟基苯甲酸甲酯

中文名称:

3,4-二羟基苯甲酸甲酯

中文同义词:

3,4-二羟基苯甲酸甲酯(CAS号:2150-43-8);原儿茶酸甲酯(3,4-二羟基苯甲酸甲酯);3,4-二羟基苯甲酸甲酯, 95+%;原儿茶酸甲酯;3,4-二羟基苯甲酸甲酯 25G;甲基原儿茶酸;3,4-二羟基苯甲酸甲酯,97%;原儿茶醛甲酯(3,4-二羟基苯甲酸甲酯)

英文名称:

Methyl 3,4-dihydroxybenzoate

英文同义词:

METHYL 3,4-DIHYDROXYBENZOATE;METHYL PROTOCATECHUATE;3,4-DIHYDROXY-BENZOIC ACID METHYL ESTER;RARECHEM AL BF 0069;3,4-dihydroxy-2-methylbenzoate;(Synonyms: Protocatechuic acid methyl ester;(SYNONYMS: PROTOCATECHUIC ACID METHYL ESTER; METHYL PROTOCATECHUATE);Methyl 3,4-dihydroxybenzoate (Synonyms: Protocatechuic acid methyl ester

CAS号:

2150-43-8

分子式:

C8H8O4

分子量:

168.15

EINECS号:

相关类别:

合成;罗氟司特-int D;原料;医药中间体;小分子抑制剂;芳烃;有机化工原料;Aromatic Esters;Aromatics, Metabolites Impurities, Pharmaceuticals, Intermediates Fine Chemicals;中药对照品;有机原料;其它酚类

Mol文件:

2150-43-8.mol

熔点 

134-135°C

沸点 

120-180 °C(Press: 1.5 Torr)

密度 

1.354±0.06 g/cm3(Predicted)

储存条件 

Inert atmosphere,Room Temperature

酸度系数(pKa)

8.19±0.18(Predicted)

BRN 

1637939

CAS 数据库

2150-43-8(CAS DataBase Reference)

NIST化学物质信息

Benzoic acid, 3,4-dihydroxy-, methyl ester(2150-43-8)

生物活性

Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的抗氧化多酚的主要代谢产物。 抗氧化和抗炎作用。

体外研究

Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) alleviates the toxic effects of F - via modulating its bioavailability, intracellular calcium level, mitochondrial membrane integrity and redox signaling in A549 cells.

体内研究

Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) (25 or 50 mg/kg bw/day) prevents the cellular F - accumulation and oxidative stress. Methyl 3,4-dihydroxybenzoate prevents the inflammatory and associated fibrosis progression by restoring the expression of RAGE and Nrf2.

化学性质 

白色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于黄连。

危险类别码 

36/37/38

安全说明 

26-36-37

海关编码 

29182900