伪原薯蓣皂苷

中文名称:

伪原薯蓣皂苷

中文同义词:

伪原薯蓣皂苷, 来源于薯蓣;伪原薯蓣皂甙;伪原薯蓣皂苷;伪薯蓣皂苷;伪原薯蓣皂苷(伪薯蓣皂苷);PSEDUOPROTODIOSCIN 伪原薯蓣皂苷

英文名称:

PROTOGRACELLIN

英文同义词:

PSEUDO-PROTODIOSCIN;PSEUDOPROTOTRIBESTIN;PROTODIOSCIN, PSEUDO-;PROTOGRACELLIN;Pseduoprotodioscin;Protogracellin, 98%, from Dioscorea opposita Thunb.;β-D-Glucopyranoside, (3β,25R)-26-(β-D-glucopyranosyloxy)furosta-5,20(22)-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-;PROTOGRACELLIN USP/EP/BP

CAS号:

102115-79-7

分子式:

C51H82O21

分子量:

1031.18

EINECS号:

相关类别:

对照品;植提标准品;中药对照品;标准品;对照品,标准品;植物提取物;黄酮;Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;对照品-中药对照品;标准品 -中药标准品;其它萜类;标准品，对照品

Mol文件:

102115-79-7.mol

密度 

1.45

储存条件 

Sealed in dry,Room Temperature

酸度系数(pKa)

12?+-.0.70(Predicted)

生物活性

Pseudoprotodioscin，一种呋喃葡糖苷，抑制 SREBP1/2 和 microRNA 33a/b 水平，降低胆固醇和甘油三酯合成相关的基因表达。

体外研究

In Hep G2 cells, Pseudoprotodioscin increases ABCA1 protein and mRNA levels, and promotes the effluxion of ApoA-1-mediated cholesterol. Pseudoprotodioscin inhibits SREBP1c and SREBP2 transcription by decreasing microRNA 33a/b levels. This procedure reciprocally lead to the increase of ABCA1 levels. In THP-1 macrophages, Pseudoprotodioscin shows the similar effect, which reduces HMGCR, FAS and ACC mRNA levels and promotes low density lipoprotein receptor by decreasing the PCSK9 levels.

化学性质 

白色结晶，溶于甲醇、水，难溶于丙酮、乙酸乙酯，来源于黄山药，穿山龙，盾叶薯蓣。

用途 

伪原薯蓣皂苷具有抗缺氧的作用。

用途 

用于含量测定/鉴定/药理实验等。 药理药效:用于心血管疾病

安全说明 

24/25

海关编码 

29389090