鸢尾苷

中文名称:

鸢尾苷

中文同义词:

鸢尾黄酮,鸢尾苷元,射干苷元;鸢尾苷元磺酸钠;鸢尾黄素(鸢尾黄酮,鸢尾苷元,射干苷元);TECTORIGENIN 鸢尾黄素;5,7-二羟基-3-(4-羟基苯基)-6-甲氧基-4H-1-苯并吡喃-4-酮;鸢尾黄素(标准品);鸢尾黄酮;射干苷元

英文名称:

Tectorigenin

英文同义词:

Tectorigenin 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one;4,5,7-Trihydroxy-6-methoxyisoflavone;Tectorigenine;Tectrigenin

CAS号:

548-77-6

分子式:

C16H12O6

分子量:

300.26

EINECS号:

相关类别:

标准品-中药标准品;中药对照品;标准品;对照品,标准品;分析标准品;植物提取物;中药标准品;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;对照品;植提标准品;分析试剂标准品;标准品-对照品;黄酮;标准品 -中药标准品;分析试剂-标准品;标准品，对照品;高纯分离试剂-标准品

Mol文件:

548-77-6.mol

熔点 

225-226°

沸点 

361.5°C (rough estimate)

密度 

1.512

折射率 

1.4600 (estimate)

储存条件 

Sealed in dry,2-8°C

酸度系数(pKa)

6.49±0.20(Predicted)

BRN 

305601

CAS 数据库

548-77-6

生物活性

Tectorigenin 是一种植物异黄酮，最初是从葛根汤干燥的花中分离出来的。

体外研究

Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria thomsonii Benth. Palmitic acid (PA)-stimulated ROS production is abolished by treatment with Tectorigenin for HUVECs in a dose-dependent manner (0.1, 1, 10 μM). Treatment with Tectorigenin attenuates enhanced IKKβ phosphorylation and effectively blocks NF-κB activation by inhibition of p65 phosphorylation at concentrations ranging from 0.1 to 10 μM. Tectorigenin treatment also effectively inhibits PA-augmented TNF-α and IL-6 production in a concentration dependent manner. The number of viable HepG2 cells treated by Tectorigenin decreases in a concentration- and time-dependent manner. When HepG2 cells are treated with Tectorigenin at 5, 10 and 20 mg/L for 24 h, the viability rate is 91%, 79% and 62%, respectively.

化学性质 

淡黄色结晶，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于植物射干的根茎。

用途 

射干苷元具有抗病毒、抗炎、解热和镇痛的作用。

用途 

用于含量测定/鉴定/药理实验等。 药理药效:具有清热解毒、利咽消痰、散血消肿的功效

WGK Germany 

3

RTECS号

NR2400000