4-氨基-N-(3-溴-4-氟苯基)-N-羟基-1,2,5-恶二唑-3-甲脒

中文名称:

4-氨基-N-(3-溴-4-氟苯基)-N-羟基-1,2,5-恶二唑-3-甲脒

中文同义词:

IDO-IN-1抑制剂;4-氨基-N-(3-溴-4-氟苯基)-N-羟基-1,2,5-恶二唑-3-甲脒;IDO抑制剂(IDO-IN-1)

英文名称:

IDO-IN-1

英文同义词:

IDO-IN-1;(Z)-4-amino-N-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide;4-Amino-N-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide;(E)-4-amino-N-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide;CS-1532;IDO-IN-1/4-Amino-N-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide;1,2,5-Oxadiazole-3-carboximidamide, 4-amino-N-(3-bromo-4-fluorophenyl)-N-hydroxy-;DO-IN-1

CAS号:

914638-30-5

分子式:

C9H7BrFN5O2

分子量:

316.09

EINECS号:

相关类别:

抑制剂;细胞生物学试剂

Mol文件:

914638-30-5.mol

沸点 

512.6±60.0 °C(Predicted)

密度 

2.03±0.1 g/cm3(Predicted)

酸度系数(pKa)

7.54±0.69(Predicted)

生物活性

IDO-IN-1是有效的IDO抑制剂，IC50为59 nM。

靶点

Target Value IDO (Cell-free assay) 59 nM

Target

Value

IDO (Cell-free assay)

59 nM