FGFR-IN-1

中文名称:

FGFR-IN-1

中文同义词:

FGFR抑制剂(FGFR-IN-1);1-[(3S)-3-[4-氨基-3-[2-(3,5-二甲氧基苯基)乙炔基]-1H-吡唑并[3,4-D]嘧啶-1-基]-1-吡咯烷基]-2-丙烯-1-酮;化合物TAS120

英文名称:

FGFR-IN-1

英文同义词:

FGFR-IN-1;FGFR-IN-1;FUTIBATINIB;TAS-120;Futibatinib;FUTIBATINIB;TAS120;TAS-120 (Futibatinib);CS-2681;CS-2344;1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-one

CAS号:

1448169-71-8

分子式:

C22H22N6O3

分子量:

418.45

EINECS号:

相关类别:

细胞生物学试剂;小分子抑制剂

Mol文件:

1448169-71-8.mol

沸点 

733.8±60.0 °C(Predicted)

密度 

1.33±0.1 g/cm3(Predicted)

酸度系数(pKa)

3.60±0.30(Predicted)

靶点

Target Value FGFR2 (Cell-free assay) 1.4 nM FGFR3 (Cell-free assay) 1.6 nM FGFR1 (Cell-free assay) 1.8 nM FGFR4 (Cell-free assay) 3.7 nM

Target

Value

FGFR2 (Cell-free assay)

1.4 nM

FGFR3 (Cell-free assay)

1.6 nM

FGFR1 (Cell-free assay)

1.8 nM

FGFR4 (Cell-free assay)

3.7 nM