N-乙酰肌肽

中文名称:

N-乙酰肌肽

中文同义词:

N-乙酰肌肽;AC-肌肽;乙酰肌肽;N乙酰肌肽/二胜肽;N-乙酰肌肽/乙酰肌肽/AC-肌肽;CARNOSINE IMPURITY 4;乙酰基肽;(S)-2-(3-乙酰氨基丙酰胺)-3-(1H-咪唑-4-基)丙酸

英文名称:

N-Acetyl carnosine

英文同义词:

(S)-2-(3-ACETYLAMINO-PROPIONYLAMINO)-3-(3H-IMIDAZOL-4-YL)-PROPIONIC ACID;n-acetyl carnosine;N-ACETYL-L-CARNOSINE;N-A-ACETYL-N-B-ALANYL-L-HISTIDINE;N-Aceyl-L-Carnosine;N-Acetyl camosine;NAC, N-a-Acetyl-N-b-alanyl-L-histidine;N-(N-acetyl-beta-alanyl)-L-histidine

CAS号:

56353-15-2

分子式:

C11H16N4O4

分子量:

268.27

EINECS号:

260-123-2

相关类别:

原料药;美容多肽;保护氨基酸及多肽类产品;添加剂;保健品原料;生物制药;医药原料药;PROTECTED AMINO ACID PEPTIDES;Amino Acids Derivatives;Heterocycles;Intermediates Fine Chemicals;Pharmaceuticals;原料;食品和饲料添加剂;医药原料

Mol文件:

56353-15-2.mol

熔点 

209-210°C

沸点 

775.9±60.0 °C(Predicted)

密度 

1.343±0.06 g/cm3(Predicted)

储存条件 

Sealed in dry,2-8°C

酸度系数(pKa)

3.08±0.10(Predicted)

生物活性

N-Acetylcarnosine 是一种天然的，含有组氨酸的二肽，是药理学上主要的 L-carnosine 的来源。N-Acetylcarnosine 是一种有效的眼科药物，有用于人类白内障的潜力。

体内研究

Right eyes of the rabbits (male grey chinchilla rabbits aged 3-4 months weighing 2-3 k) are instilled with 80 μL of formulation A containing 1 % N-Acetylcarnosine. The N-Acetylcarnosine prodrug eye drops optimize the clinical effects for the treatment of ophthalmic disorders (such as prevention and reversal of cataracts in human and animal eyes).