4-羟基扁桃酸

中文名称:

4-羟基扁桃酸

中文同义词:

对羟基扁桃酸(一水合物形式);4-羟基扁桃酸;对羟基扁桃酸

英文名称:

4-Hydroxyphenylglycolic acid

英文同义词:

RARECHEM AL BO 0522;P-HYDROXY MANDELIC ACID;4-HYDROXYMANDELIC ACID 97% HPLC;(4-Hydroxyphenyl)hydroxyacetic acid;2-(4-Hydroxyphenyl)-2-hydroxyacetic acid;4,α-Dihydroxybenzeneacetic acid;DL-4-Hydroxymandelic acid,95%;2-hydroxy-2-(4-hydroxyphenyl)acetic acid hydrate

CAS号:

1198-84-1

分子式:

C8H8O4

分子量:

168.15

EINECS号:

214-839-7

相关类别:

医药中间体;有机原料;中间体

Mol文件:

1198-84-1.mol

熔点 

82-85 °C(lit.)

沸点 

405.4±30.0 °C(Predicted)

密度 

1.480±0.06 g/cm3(Predicted)

酸度系数(pKa)

3.51±0.10(Predicted)

CAS 数据库

1198-84-1(CAS DataBase Reference)

EPA化学物质信息

Benzeneacetic acid, ?,4-dihydroxy- (1198-84-1)

生物活性

p-Hydroxymandelic acid 是一种有价值的芳香类化学品，广泛用于生产药物和食品添加剂。

靶点

Human Endogenous Metabolite

Human Endogenous Metabolite

体外研究

p-Hydroxymandelic acid (4-Hydroxymandelic acid; 4-HMA) is widely used in production of aromatic drugs and flavors. It is employed for the preparation of 4-hydroxyphenylacetic acid, which is the synthetic precursor of selective β1-receptor antagonist drug atenolol. p-Hydroxymandelic acid can conjugate cytotoxic drug and enzyme substrate, and such a p-Hydroxymandelic acid based adaptor system showed promising application in the targeting drug delivery system.

化学性质 

淡黄色水合物固体。熔点95-97℃。

危险品标志 

Xi

危险类别码 

36/37/38

安全说明 

26-36

WGK Germany 

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