去氧皮质酮新戊酸酯

中文名称:

去氧皮质酮新戊酸酯

中文同义词:

去氧皮质酮新戊酸酯;特戊酸去氧皮质酮;孕甾-4-烯-3,20-二酮,21-(2,2-二甲基-1-丙酸)酯;去氧皮质酮新戊酸酯 USP标准品

英文名称:

Desoxycorticosterone pivalate

英文同义词:

11-deoxycorticosterone,pivalate;docp;neodin-depositum;percortenm;percortenpivalate;21-hydroxy-4-pregnene-3,20-dione pivalate;4-PREGNEN-21-OL-3,20-DIONE TRIMETHYL ACETATE;desoxycortone pivalate

CAS号:

808-48-0

分子式:

C26H38O4

分子量:

414.58

EINECS号:

212-366-0

相关类别:

医药原料;Intermediates Fine Chemicals;Pharmaceuticals;Steroids

Mol文件:

808-48-0.mol

熔点 

198-204°C

沸点 

529.0±50.0 °C(Predicted)

密度 

1.11±0.1 g/cm3(Predicted)

CAS 数据库

808-48-0(CAS DataBase Reference)

生物活性

Desoxycorticosterone pivalate (DOCP) 是一种盐皮质激素，是地塞米松的类似物。Desoxycorticosterone pivalate 用于犬肾上腺皮质功能减退症的研究。

体内研究

A starting dosage of 1.5 mg/kg Desoxycorticosterone pivalate (DOCP) is effective in controlling clinical signs and serum electrolyte concentrations in the majority of dogs with PH. An additional dose reduction often is needed to maintain an injection interval of 28-30 days. Young and growing animals seem to need higher dosages.

化学性质 

白色或类白色结晶性粉末。熔点200-206℃。

海关编码 

2937290000