N-甲基-N,N-双(2-吡啶基乙基)胺

中文名称:

N-甲基-N,N-双(2-吡啶基乙基)胺

中文同义词:

倍他司汀EP杂质C;N-甲基-N,N-双(2-吡啶基乙基)胺;倍他司汀杂质C(EP);盐酸倍他司汀EP杂质C 三盐酸盐;盐酸倍他司汀EP杂质C 三甲磺酸盐;倍他司汀EP杂质C盐酸盐;化合物NSC19005

英文名称:

N-Methyl-N,N-bis(2-pyridylethyl)amine

英文同义词:

N-methyl-2-(pyridin-2-yl)-N-(2-(pyridin-2-yl)ethyl)ethanamine;Betahistine EP Impurity C;NSC19005;Methylbis(2-pyridylethyl)aMine;N-Methylbis[2-(2-pyridylethyl)]aMine;N-Methyl-N,N-bis(2-pyridylethyl)aMine;N-Methyl-N-[2-(2-pyridinyl)ethyl]-2-pyridineethanaMine;N-METHYL-N-[2-(2-PYRIDINYL)ETHYL]-2-PYRIDINEETHANAMINE;METHYLBIS(2-PYRIDYLETHYL)AMINE;N-METHYLBIS[2-(2-PYRIDYLETHYL)]AMINE;NSC 19005;

CAS号:

5452-87-9

分子式:

C15H19N3

分子量:

241.33

EINECS号:

相关类别:

Amines;Aromatics;Heterocycles;Intermediates

Mol文件:

5452-87-9.mol

沸点 

126-127 °C(Press: 0.08 Torr)

密度 

1.067±0.06 g/cm3(Predicted)

储存条件 

Sealed in dry,Room Temperature

酸度系数(pKa)

8.17±0.50(Predicted)

生物活性

Betahistine EP Impurity C (NSC19005) 是 Betahistine 的杂质。 Betahistine 是一种口服有效的组胺 H1 受体激动剂和 H3 受体拮抗剂，用于研究类风湿关节炎 (RA)。

体外研究

Betahistine (0-10 μM) inhibits [ 125 I]iodoproxyfan binding to membranes of CHO (rH 3(445) R) and CHO (hH 3(445) R) cells with IC 50 values of 1.9 μM and 3.3 μM, respectively. Lead to K i values of 1.4 μM and 2.5 μM, respectively.