假尿苷

中文名称:

假尿苷

中文同义词:

5-Β-D-核呋喃基尿嘧啶;Β-假尿苷;假尿苷;Β-PSEUDOURIDINE;5-Β-D-核呋喃基尿嘧啶;Β-假尿苷

英文名称:

BETA-PSEUDOURIDINE

英文同义词:

PSEUDOURIDINE;5-b-D-ribofuranosyl-2,4(1H,3H)-Pyrimidinedione;5-β-D-ribofuranosyluracil;BETA-PSEUDOURIDINE;B-Pseudouridine;5-β-D-Ribofuranosyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;5-β-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione;Pseudouridine C

CAS号:

1445-07-4

分子式:

C9H12N2O6

分子量:

244.2

EINECS号:

相关类别:

核苷;修饰性核苷;化学试剂;医用原料;生化试剂;医药原料;Bases Related Reagents;Carbohydrates Derivatives;Heterocycles;Nucleotides;医药、农药及染料中间体;Pharmaceutical;常用糖合成中间体

Mol文件:

1445-07-4.mol

熔点 

222 °C

密度 

1.641±0.06 g/cm3(Predicted)

酸度系数(pKa)

8.52±0.10(Predicted)

最大波长(λmax)

264nm(MeOH)(lit.)

生物活性

Pseudouridine，非编码 RNA 中最丰富的修饰核苷，通过稳定 RNA 结构增强转移 RNA 和核糖体 RNA 的功能。

靶点

Human Endogenous Metabolite

Human Endogenous Metabolite

用途 

An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called 唯 synthases, which post-transcriptionally isomerize specific uridine res idues in RNA in a process termed pseudouridylation. Studies suggest that β-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes.