中文同义词:
大波斯菊苷,芹菜素-7-葡萄糖苷,芹菜素-7-O-Β-D-葡萄糖苷;芹黄素-7-葡糖苷;芹菜素-7-O-Β-D-吡喃葡萄糖苷(大波斯菊苷,芹菜素-7-葡萄糖苷,芹菜素-7-O-Β-D-葡萄糖苷);芹菜素7-O-葡糖苷;芹菜素-7-O-Β-D-葡萄吡喃糖苷;大波斯菊苷,芹菜素-7-O-Β-D-吡喃葡萄糖苷(标准品);APIGENIN-7-O-Β-D-GLUCOPYRANOSIDE 芹菜素-7-O-Β-D-吡喃葡萄糖苷;芹菜素-7-0-葡萄糖苷
英文名称:
Apigenin 7-glucoside
英文同义词:
COSMETIN;4H-1-Benzopyran-4-one,7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl);Apigenin 7-beta-D-glucoside;Apigenin 7-glucoside SynonyMs:Apigetrin;Apigenin 7-b-D-glucoside;4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-;Apigenin 7-glucoside, >=98%;Apigetrin(Apigenin-7-O-glucoside)
相关类别:
中草药成分;标准品-中药标准品;标准品-对照品;分析对照品;标准品;对照品;Tri-substituted Flavones;Pharmaceutical intermediate;植物提取物;chemical reagent;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;中药对照品;植提标准品;黄酮;标准品 -中药标准品;标准品，对照品;Flavones
沸点
788.9±60.0 °C(Predicted)
密度
1.642±0.06 g/cm3(Predicted)
酸度系数(pKa)
6.13±0.40(Predicted)
CAS 数据库
578-74-5(CAS DataBase Reference)
生物活性
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside)，ROS 清除剂，具有抗增殖，抗氧化活性。
体外研究
Apigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucoside provoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucoside enhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells.
Apigenin 7-glucoside specifically induces the differentiation of CD34 + cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner.
化学性质
白色结晶体，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于广藿香、仙鹤草，蓰草，构树叶。
用途
用于含量测定/鉴定/药理实验等。
药理药效:抗肿瘤、消炎、抗病毒。
