中文同义词:
异樱花亭;异樱花亭(异樱花亭苷);异樱花亭(异樱花素);5,7-二羟基-4-甲氧基黄烷酮;异野樱素;异樱花亭苷;异樱花素;异樱花素,异樱花亭(异樱花亭苷)
英文同义词:
5,7-DIHYDROXY-4-METHOXYFLAVANONE;ISOSAKURANETIN;(S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone;ISOSAKURANETIN(P);5,7-DIHYDROXY-4-METHOXYFLAVANONE hplc;ISOSAKURANETIN WITH HPLC;(2S)-5,7-Dihydroxy-4-methoxyflavanone;(S)-2,3-Dihydro-2-(4-methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
相关类别:
对照品标准品;对照品;中药对照品;植物提取物;标准品;分析试剂标准品;对照品-中药对照品;Flavanones;Flavonoids;黄酮;标准品 -中药标准品;标准品，对照品
沸点
539.2±50.0 °C(Predicted)
密度
1.370±0.06 g/cm3(Predicted)
酸度系数(pKa)
7.50±0.40(Predicted)
产品描述
异樱花亭是一种白色针晶(氯仿-甲醇)，溶于氯仿、甲醇、丙酮、乙酸乙酯、DMSO。紫外灯365nm下显绿色荧光，盐酸镁粉反应呈阳性，浓硫酸-香草醛反应显橙红色。
生物活性
Isosakuranetin 是可以在 Citrus bergamia 的果实中找到的黄烷酮黄酮类化合物。
体外研究
Isosakuranetin stimulates melanin accumulation in a dose-dependent manner. In addition, Isosakuranetin at 30 μM gradually increases the expression of Tyr, TRP1, and TRP2 after 48 and 72 h. The MTT assay shows that Isosakuranetin decreases the number of cells at concentrations greater than 45 μM. Further analysis of trypan blue staining demonstrates that Isosakuranetin does not affect the viability of B16 melanocytes, but shows that Isosakuranetin decreases their proliferation rate. The tyrosinase activity of B16 melanocytes treated with 15 and 30 μM Isosakuranetin for 72 h is significantly increased by 2- and 3.2-fold, respectively, in comparison with that of the control cells.
体内研究
Isosakuranetin dose-dependently increases the paw-withdrawal threshold within the dose range of 1.5 to 6 mg/kg. Post hoc analysis reveals that Isosakuranetin increases the paw-withdrawal threshold and statistical significance is seen at times 30 and 40 min for the dose of 3 mg/kg and 30 to 60 min for the dose of 6 mg/kg.
化学性质
黄色结晶性粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于飞机草，蔷薇科樱属植物樱花Prunus serrulata。
