中文名称:

绞股蓝皂苷 LXXV

中文同义词:

绞股蓝皂苷 LXXV

英文名称:

β-D-Glucopyranoside, (3β,12β)-3,12-dihydroxydammar-24-en-20-yl 6-O-β-D-glucopyranosyl-

英文同义词:

β-D-Glucopyranoside, (3β,12β)-3,12-dihydroxydammar-24-en-20-yl 6-O-β-D-glucopyranosyl-;Gypenoside LXXV

CAS号:

110261-98-8

分子式:

C42H72O13

分子量:

785.01

EINECS号:

相关类别:

对照品;标准品-对照品;标准品，对照品

Mol文件:

Mol File

沸点 

879.6±65.0 °C(Predicted)

密度 

1.30±0.1 g/cm3(Predicted)

酸度系数(pKa)

12.90±0.70(Predicted)

生物活性

Gypenoside LXXV 是从绞股蓝中分离出来的，是人参皂甙 Rb1 的去糖基化形式之一。Gypenoside LXXV 显著降低癌细胞活力并显示出有效的抗癌作用。

体外研究

Gypenoside LXXV (1.0-100 μM; for 48 hours) reduces proliferation in a dose-dependent manner. Cell Viability Assay Cell Line: Three cancer cell lines (HeLa (cervical cancer cell line), B16 (melanoma cell line), and MDA-MB231 (human breast cancer cell line) Concentration: 1.0-100 μM Incubation Time: For 48 hours Result: Reduced proliferation in a dose-dependent manner and inhibited almost all cancer cells at 50 μM.

Cell Line:

Three cancer cell lines (HeLa (cervical cancer cell line), B16 (melanoma cell line), and MDA-MB231 (human breast cancer cell line)

Concentration:

1.0-100 μM

Incubation Time:

For 48 hours

Result:

Reduced proliferation in a dose-dependent manner and inhibited almost all cancer cells at 50 μM.