吡咯他尼

中文名称:

吡咯他尼

中文同义词:

4-苯氧基-3-吡咯烷-1-基-5-氨基磺酰基苯甲酸;苯氧吡酸;吡咯速尿;吡咯他尼;吡咯烷胺杂质;吡咯他尼 EP标准品;吡咯他尼系统适应性 EP标准品;哌替尼

英文名称:

Piretanide

英文同义词:

PIRETANIDE;4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoyl-benzoic acid;4-Phenoxy-3-(pyrrolidinyl)-5-sulfamoylbenzoic acid;4-Phenoxy-3-(1-pyrrolidinyl)-5-sulfamoylbenzoic acid;HOE 118;hoe-118;S 734118;S-73-4118

CAS号:

55837-27-9

分子式:

C17H18N2O5S

分子量:

362.4

EINECS号:

259-852-9

相关类别:

泌尿系统药物;医药与生物化工;原料药;医药原料药;利尿药物;Pharmaceuticals;Sulfur Selenium Compounds;Amines;Aromatics;Heterocycles;Intermediates Fine Chemicals

Mol文件:

55837-27-9.mol

熔点 

225-227°

沸点 

253°C (rough estimate)

密度 

1.3049 (rough estimate)

折射率 

1.6510 (estimate)

储存条件 

Sealed in dry,2-8°C

溶解度 

Very slightly soluble in water, sparingly soluble in anhydrous ethanol. It shows polymorphism (5.9).

酸度系数(pKa)

10.22±0.60(Predicted)

形态

neat

颜色

Pale-yellow platelets from MeOH (aq)

CAS 数据库

55837-27-9(CAS DataBase Reference)

毒性

LD50 in rats, mice (mg/kg): 5601, 3672 orally (Merkel)